Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 3/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553207 | 0.87 | P2RY12 (0.42) | NR3C1ALDH1A1THRBSMN1; SMN2STS | |
| SCHEMBL8554113 | 0.84 | FPR1 (0.47) | NR3C1ALDH1A1THRBSMN1; SMN2P2RY12 | |
| SCHEMBL1984012 | 0.78 | NTRK1 (0.48) | ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL8555714 | 0.78 | NR3C1 (0.45) | NR3C1ACHEP2RX7 | |
| SCHEMBL8554531 | 0.76 | MAPT (0.43) | ALDH1A1THRBSMN1; SMN2P2RY12 | |
| SCHEMBL8553758 | 0.76 | ALDH1A1 (0.46) | ALDH1A1HTTTHRBSMN1; SMN2P2RY12 | |
| SCHEMBL8552593 | 0.74 | MAPT (0.41) | NR3C1ALDH1A1THRBSMN1; SMN2P2RY12 | |
| SCHEMBL8555738 | 0.74 | TDP1 (0.44) | NR3C1ALDH1A1THRBSMN1; SMN2P2RY12 | |
| SCHEMBL8553085 | 0.73 | ALDH1A1 (0.43) | ALDH1A1THRBSMN1; SMN2P2RY12 | |
| SCHEMBL8554183 | 0.72 | TSHR (0.58) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |