Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556278 | 0.86 | NTRK1 (0.43) | NTRK1MEN1KMT2APOLBNPSR1 | |
| SCHEMBL1984012 | 0.79 | NTRK1 (0.48) | PTGESNTRK1POLBMAPTALDH1A1 | |
| SCHEMBL8553385 | 0.77 | ALDH1A1 (0.42) | PTGESMEN1KMT2APOLBNPSR1 | |
| SCHEMBL29721664 | 0.77 | NTRK1 (0.43) | NTRK1MEN1KMT2APOLBMAPT | |
| SCHEMBL8555334 | 0.72 | MAPT (0.46) | PTGESMEN1KMT2APOLBMAPT | |
| SCHEMBL8550650 | 0.71 | FPR1 (0.53) | NTRK1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL8551653 | 0.71 | NTRK1 (0.53) | NTRK1POLBNPSR1MAPTALDH1A1 | |
| SCHEMBL8553095 | 0.70 | ALDH1A1 (0.46) | PTGESMEN1KMT2APOLBMAPT | |
| SCHEMBL8553146 | 0.70 | NTRK1 (0.54) | NTRK1TP53POLBMAPTALDH1A1 | |
| SCHEMBL8552895 | 0.70 | FPR1 (0.48) | NTRK1POLBNPSR1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | claimed |
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |