Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PTGES2 | Q9H7Z7 | 10/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560882 | 0.96 | MAPT (0.43) | MAPTPTGES2RXRAKAT6AALDH1A1 | |
| SCHEMBL8559042 | 0.90 | L3MBTL1 (0.43) | MAPTRXRAALDH1A1CA12CA1 | |
| SCHEMBL8559802 | 0.89 | RXRA (0.49) | MAPTPTGES2RXRAALDH1A1SCN9A | |
| SCHEMBL8554229 | 0.89 | CDK9 (0.42) | RXRACA12CA1CA2CA9 | |
| SCHEMBL8553816 | 0.87 | MAPT (0.40) | MAPTRXRAALDH1A1LMNAP2RX3 | |
| SCHEMBL8561449 | 0.87 | RXRA (0.40) | MAPTPTGES2RXRAALDH1A1LMNA | |
| SCHEMBL7499023 | 0.86 | CA2 (0.43) | MAPTRXRAALDH1A1LMNACA12 | |
| SCHEMBL8557664 | 0.86 | L3MBTL1 (0.43) | MAPTRXRAALDH1A1CA12CA1 | |
| SCHEMBL8553420 | 0.85 | MAPT (0.40) | MAPTRXRAALDH1A1LMNACA12 | |
| SCHEMBL8556401 | 0.85 | CYP2C9 (0.40) | MAPTPTGES2RXRAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |