Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.45 |
| ▸ | TP53 | P04637 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | THRB | P10828 | 4/20 | 0.45 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8552279 | 0.82 | MEN1 (0.38) | THRB | |
| SCHEMBL8553647 | 0.80 | LMNA (0.43) | LMNATP53MAPTTHRB | |
| SCHEMBL8625016 | 0.79 | KDM4E (0.49) | LMNATP53MAPT | |
| SCHEMBL8590974 | 0.78 | L3MBTL1 (0.44) | LMNATP53MAPTTHRB | |
| SCHEMBL8550488 | 0.77 | KDM4E (0.44) | MAPTTHRB | |
| SCHEMBL8553020 | 0.75 | THRB (0.46) | MAPTTHRB | |
| SCHEMBL8552358 | 0.75 | GLS (0.46) | — | |
| SCHEMBL8549545 | 0.74 | L3MBTL1 (0.43) | LMNAMAPTTHRB | |
| SCHEMBL17271545 | 0.73 | RECQL (0.50) | MAPT | |
| SCHEMBL8551331 | 0.73 | POLB (0.43) | LMNAMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858457-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | Dr. Karl Thomae GmbH (DE) | 1998-08-19 | — | — | EP | disclosed |
| WO-1997015567-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | DR. KARL THOMAE GMBH (DE) | 1997-05-01 | — | — | WO | disclosed |