Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549939 | 0.85 | ALDH1A1 (0.33) | BRAF | |
| SCHEMBL7141353 | 0.84 | HTR1F (0.36) | — | |
| SCHEMBL8552959 | 0.75 | KDM4E (0.43) | — | |
| SCHEMBL8549554 | 0.73 | HTR6 (0.42) | — | |
| SCHEMBL8553478 | 0.66 | MAPT (0.37) | — | |
| SCHEMBL8550531 | 0.66 | EGFR (0.42) | — | |
| SCHEMBL8550889 | 0.65 | HTR6 (0.38) | — | |
| SCHEMBL8548267 | 0.65 | KDM4E (0.41) | — | |
| SCHEMBL8708853 | 0.61 | CNR2 (0.41) | — | |
| SCHEMBL7147572 | 0.60 | MAPT (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998015545-A1 | NEW SEROTONIN 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-04-16 | — | — | WO | disclosed |
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |