Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | F13A1 | P00488 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | TGM1 | P22735 | 1/20 | 0.33 |
| ▸ | ITK | Q08881 | 1/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 5/20 | 0.31 |
| ▸ | DPEP1 | P16444 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8153200 | 1.00 | ALDH1A1 (0.35) | ALDH1A1LMNAMAPTCYP2C9F13A1 | |
| SCHEMBL8550400 | 0.83 | TGM2 (0.38) | ALDH1A1F13A1TGM2TGM1ITK | |
| SCHEMBL8547481 | 0.78 | TGM2 (0.43) | ALDH1A1LMNAMAPTCYP2C9TGM2 | |
| SCHEMBL8555056 | 0.76 | THRB (0.43) | ALDH1A1CYP2C9TGM2ZDHHC20ZDHHC2 | |
| SCHEMBL8150628 | 0.76 | CA1 (0.33) | ALDH1A1LMNAMAPTCYP2C9DPEP1 | |
| SCHEMBL8551807 | 0.75 | TGM2 (0.43) | ALDH1A1LMNAMAPTTGM2DPEP1 | |
| SCHEMBL8546748 | 0.75 | ESR2 (0.36) | ALDH1A1LMNA | |
| SCHEMBL8554406 | 0.75 | ACACB (0.43) | ALDH1A1LMNAMAPT | |
| SCHEMBL8546509 | 0.75 | TGM2 (0.47) | ALDH1A1LMNAMAPTTGM2 | |
| SCHEMBL8550291 | 0.72 | ALDH1A1 (0.39) | ALDH1A1LMNAMAPTCYP2C9TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |