Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | FBP1 | P09467 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552485 | 0.87 | ALDH1A1 (0.34) | ALDH1A1TSHRMAPK1TDP1TGM2 | |
| SCHEMBL8555909 | 0.84 | EGFR (0.33) | ALDH1A1KDM4EKMT2APKMMAPT | |
| SCHEMBL8547481 | 0.83 | TGM2 (0.43) | ALDH1A1KMT2AHDAC2MAPTMEN1 | |
| SCHEMBL8551807 | 0.83 | TGM2 (0.43) | ALDH1A1KMT2AMAPTMEN1LMNA | |
| SCHEMBL8593809 | 0.82 | FBP1 (0.40) | ALDH1A1KDM4EKMT2APKMATM | |
| SCHEMBL8554406 | 0.80 | ACACB (0.43) | ALDH1A1KDM4EKMT2AMAPTRAB9A | |
| SCHEMBL8549416 | 0.80 | TGM2 (0.47) | HDAC2LMNATGM2 | |
| SCHEMBL8546509 | 0.80 | TGM2 (0.47) | ALDH1A1KDM4EKMT2APKMHDAC2 | |
| SCHEMBL8547085 | 0.79 | PDCD1 (0.43) | KMT2AHDAC2FBP1TGM2 | |
| SCHEMBL8553499 | 0.79 | TGM2 (0.48) | ALDH1A1KDM4EKMT2APKMFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |