Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8546509 | 0.88 | TGM2 (0.47) | MAPTLMNARAB9AALDH1A1KDM4E | |
| SCHEMBL8548995 | 0.84 | ALOX5 (0.42) | ACACBMAPTLMNAALOX5NPC1 | |
| SCHEMBL8547481 | 0.83 | TGM2 (0.43) | MAPTLMNANPC1RAB9AALDH1A1 | |
| SCHEMBL8555056 | 0.81 | THRB (0.43) | ALOX5NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL8551807 | 0.81 | TGM2 (0.43) | MAPTLMNAALDH1A1HTTKMT2A | |
| SCHEMBL8550291 | 0.80 | ALDH1A1 (0.39) | MAPTLMNARAB9AALDH1A1KDM4E | |
| SCHEMBL8549416 | 0.78 | TGM2 (0.47) | LMNASMN1; SMN2 | |
| SCHEMBL8550135 | 0.77 | ALDH1A1 (0.47) | MAPTLMNANPC1RAB9AALDH1A1 | |
| SCHEMBL8551267 | 0.77 | ZDHHC20 (0.42) | LMNAALOX5EGFR | |
| SCHEMBL8553499 | 0.77 | TGM2 (0.48) | MAPTLMNAALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |