Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.43 |
| ▸ | TGM2 | P21980 | 3/20 | 0.41 |
| ▸ | THRA | P10827 | 2/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547481 | 0.84 | TGM2 (0.43) | TGM2ZDHHC20ZDHHC2L3MBTL1ALDH1A1 | |
| SCHEMBL8551267 | 0.82 | ZDHHC20 (0.42) | THRBTGM2THRAZDHHC20ZDHHC2 | |
| SCHEMBL8551807 | 0.82 | TGM2 (0.43) | TGM2ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL8554406 | 0.81 | ACACB (0.43) | ALOX5ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8546509 | 0.81 | TGM2 (0.47) | THRBTGM2ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL8550291 | 0.79 | ALDH1A1 (0.39) | TGM2L3MBTL1ALDH1A1RAB9ACYP3A4 | |
| SCHEMBL8549416 | 0.79 | TGM2 (0.47) | TGM2PPARGSMN1; SMN2 | |
| SCHEMBL8553499 | 0.78 | TGM2 (0.48) | TGM2ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL8153200 | 0.76 | ALDH1A1 (0.35) | TGM2ZDHHC20ZDHHC2ALDH1A1CYP2C9 | |
| SCHEMBL8554299 | 0.76 | ALDH1A1 (0.35) | TGM2ZDHHC20ZDHHC2ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |