Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 4/20 | 0.48 |
| ▸ | DRD3 | P35462 | 3/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | SMO | Q99835 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559788 | 0.82 | MAPT (0.50) | MAPTALDH1A1KDM4EHTTTDP1 | |
| SCHEMBL8555562 | 0.82 | DRD4 (0.54) | MAPTALDH1A1KDM4EHTTDRD2 | |
| SCHEMBL8555604 | 0.80 | MAPT (0.65) | MAPTALDH1A1TDP1DRD2LMNA | |
| SCHEMBL7481150 | 0.74 | ALDH1A1 (0.41) | MAPTALDH1A1KDM4EHTTTDP1 | |
| SCHEMBL8353109 | 0.72 | DRD2 (0.75) | MAPTALDH1A1KDM4EHTTTDP1 | |
| SCHEMBL8556657 | 0.72 | MEN1 (0.51) | ALDH1A1KDM4EDRD2KMT2AHSD17B10 | |
| SCHEMBL11923385 | 0.72 | SIGMAR1 (0.79) | MAPTALDH1A1TDP1DRD2LMNA | |
| SCHEMBL8555169 | 0.71 | DRD2 (0.38) | ALDH1A1DRD2KMT2AMEN1 | |
| SCHEMBL6030381 | 0.71 | ALDH1A1 (0.72) | MAPTALDH1A1KDM4EDRD2LMNA | |
| Hydrochloric Acid SCHEMBL11213408 | 0.71 | SIGMAR1 (0.77) | MAPTALDH1A1TDP1DRD2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883622-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1998-12-16 | — | — | EP | claimed |
| EP-0883606-A1 | PROCESS FOR SCAVENGING THIOLS | APOTEX INC. (CA) | 1998-12-16 | — | — | EP | claimed |
| WO-1997031923-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1997-09-04 | — | — | WO | claimed |
| WO-1997031893-A1 | PROCESS FOR SCAVENGING THIOLS | APOTEX INC. (CA) | 1997-09-04 | — | — | WO | claimed |