Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 3/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP5 | P51878 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556503 | 0.83 | SIGMAR1 (0.58) | SIGMAR1ALDH1A1DRD4KMT2A | |
| SCHEMBL8357217 | 0.80 | ALDH1A1 (0.82) | SIGMAR1ALDH1A1TSHRDRD4GAA | |
| SCHEMBL8558558 | 0.78 | MAPT (0.61) | SIGMAR1ALDH1A1TSHRDRD4GAA | |
| SCHEMBL28511718 | 0.78 | ALDH1A1 (0.60) | SIGMAR1ALDH1A1TSHRDRD4CASP1 | |
| SCHEMBL15807699 | 0.78 | ALDH1A1 (0.63) | SIGMAR1ALDH1A1TSHRDRD4CASP1 | |
| SCHEMBL3763284 | 0.76 | CASP1 (0.55) | SIGMAR1ALDH1A1TSHRDRD4CASP1 | |
| SCHEMBL8668935 | 0.76 | LMNA (0.55) | SIGMAR1ALDH1A1TSHRGAAMEN1 | |
| SCHEMBL11384876 | 0.76 | CASP1 (0.66) | SIGMAR1ALDH1A1TSHRDRD4CASP1 | |
| SCHEMBL8188324 | 0.75 | SIGMAR1 (1.00) | SIGMAR1DRD4KMT2A | |
| SCHEMBL2489199 | 0.75 | SIGMAR1 (1.00) | SIGMAR1DRD4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883622-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1998-12-16 | — | — | EP | disclosed |
| EP-0883606-A1 | PROCESS FOR SCAVENGING THIOLS | APOTEX INC. (CA) | 1998-12-16 | — | — | EP | disclosed |
| WO-1997031923-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1997-09-04 | — | — | WO | disclosed |
| WO-1997031893-A1 | PROCESS FOR SCAVENGING THIOLS | APOTEX INC. (CA) | 1997-09-04 | — | — | WO | disclosed |