Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 10/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558370 | 0.83 | ALDH1A1 (0.53) | LMNAALDH1A1TSHRCYP3A4HIF1A | |
| SCHEMBL2579539 | 0.79 | LMNA (0.72) | LMNAALDH1A1TSHRKDM4ECYP3A4 | |
| SCHEMBL28492580 | 0.76 | KDM4E (0.61) | LMNAALDH1A1TSHRKDM4ECYP3A4 | |
| SCHEMBL8555816 | 0.76 | SIGMAR1 (0.56) | ALDH1A1TSHRKDM4EGAASIGMAR1 | |
| SCHEMBL8558558 | 0.73 | MAPT (0.61) | LMNAALDH1A1TSHRNPSR1MAPK1 | |
| SCHEMBL11036914 | 0.72 | LTA4H (0.77) | LMNAALDH1A1TSHRKDM4ECYP3A4 | |
| SCHEMBL613704 | 0.72 | LTA4H (0.77) | LMNAALDH1A1TSHRKDM4ECYP3A4 | |
| SCHEMBL14433472 | 0.72 | LMNA (0.57) | LMNAALDH1A1TSHRKDM4ECYP3A4 | |
| SCHEMBL7261524 | 0.71 | LMNA (0.62) | LMNAALDH1A1TSHRKDM4ECYP3A4 | |
| SCHEMBL43559 | 0.71 | LMNA (0.58) | LMNAALDH1A1TSHRKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883606-A1 | PROCESS FOR SCAVENGING THIOLS | APOTEX INC. (CA) | 1998-12-16 | — | — | EP | claimed |
| WO-1997031893-A1 | PROCESS FOR SCAVENGING THIOLS | APOTEX INC. (CA) | 1997-09-04 | — | — | WO | claimed |