Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4903950 | 0.76 | CTNNB1 (0.58) | CES1CES2AKR1B1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9054439 | 0.69 | KDM4E (0.52) | CES1CES2AKR1B1SMN1; SMN2ALDH1A1 | |
| SCHEMBL672320 | 0.68 | CES2 (0.47) | CES1CES2AKR1B1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7129795 | 0.66 | MEN1 (0.62) | CES1CES2AKR1B1ALDH1A1MAPT | |
| SCHEMBL24800 | 0.66 | MAPT (0.73) | CES1CES2AKR1B1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7129800 | 0.66 | MAPT (0.80) | CES1CES2AKR1B1SMN1; SMN2GAA | |
| Phenylacetic Acid SCHEMBL6930087 | 0.66 | AKR1B1 (0.94) | CES1CES2AKR1B1GAAPOLB | |
| Phenylacetic Acid SCHEMBL4441542 | 0.66 | AKR1B1 (0.94) | CES1CES2AKR1B1GAAMAPT | |
| SCHEMBL1515752 | 0.66 | LMNA (0.59) | CES1CES2AKR1B1SMN1; SMN2ALDH1A1 | |
| SCHEMBL165353 | 0.66 | PLA2G4A (0.66) | CES1CES2AKR1B1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883622-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1998-12-16 | — | — | EP | disclosed |
| WO-1997031923-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1997-09-04 | — | — | WO | disclosed |