Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 9/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559788 | 0.85 | MAPT (0.50) | DRD4LMNARECQLKMT2ASMN1; SMN2 | |
| SCHEMBL8556503 | 0.84 | SIGMAR1 (0.58) | DRD4LMNAKMT2ADRD3ALDH1A1 | |
| SCHEMBL8555924 | 0.82 | MAPT (0.53) | DRD4LMNAKMT2AGAADRD3 | |
| SCHEMBL8558421 | 0.81 | ALDH1A1 (0.55) | DRD4LMNAKMT2ASMN1; SMN2DRD3 | |
| SCHEMBL8556657 | 0.80 | MEN1 (0.51) | DRD4KMT2ADRD3KDM4EALDH1A1 | |
| SCHEMBL8558558 | 0.77 | MAPT (0.61) | DRD4LMNARECQLKMT2ASMN1; SMN2 | |
| SCHEMBL8558370 | 0.76 | ALDH1A1 (0.53) | LMNAKMT2ASMN1; SMN2GAADRD3 | |
| SCHEMBL7481150 | 0.76 | ALDH1A1 (0.41) | KMT2ASMN1; SMN2GAAKDM4EALDH1A1 | |
| SCHEMBL8557359 | 0.76 | CXCR4 (0.43) | KMT2ASMN1; SMN2GAAALDH1A1HTT | |
| SCHEMBL8555816 | 0.74 | SIGMAR1 (0.56) | DRD4KMT2AGAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883622-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1998-12-16 | — | — | EP | claimed |
| WO-1997031923-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1997-09-04 | — | — | WO | claimed |
| EP-0883622-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1998-12-16 | — | — | EP | disclosed |
| EP-0883606-A1 | PROCESS FOR SCAVENGING THIOLS | APOTEX INC. (CA) | 1998-12-16 | — | — | EP | disclosed |
| WO-1997031923-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1997-09-04 | — | — | WO | disclosed |
| WO-1997031893-A1 | PROCESS FOR SCAVENGING THIOLS | APOTEX INC. (CA) | 1997-09-04 | — | — | WO | disclosed |