Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558421 | 0.82 | ALDH1A1 (0.55) | KMT2AKDM4EALDH1A1POLBTSHR | |
| SCHEMBL8555562 | 0.80 | DRD4 (0.54) | KMT2AKDM4EALDH1A1NPSR1DRD2 | |
| SCHEMBL8674633 | 0.79 | LMNA (0.52) | MEN1KMT2AKDM4EALDH1A1POLB | |
| SCHEMBL8557359 | 0.77 | CXCR4 (0.43) | MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL7481150 | 0.77 | ALDH1A1 (0.41) | MEN1KMT2AKDM4EALDH1A1POLB | |
| SCHEMBL8556503 | 0.76 | SIGMAR1 (0.58) | KMT2AALDH1A1POLBHSD17B10DRD2 | |
| SCHEMBL8559788 | 0.75 | MAPT (0.50) | MEN1KMT2AKDM4EALDH1A1POLB | |
| SCHEMBL8560517 | 0.74 | CYP2C19 (0.40) | MEN1KMT2AKDM4EALDH1A1POLB | |
| SCHEMBL8555169 | 0.74 | DRD2 (0.38) | MEN1KMT2AALDH1A1DRD2 | |
| SCHEMBL1876523 | 0.73 | MEN1 (0.87) | MEN1KMT2AKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883622-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1998-12-16 | — | — | EP | claimed |
| WO-1997031923-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1997-09-04 | — | — | WO | claimed |