Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | GFER | P55789 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555562 | 0.85 | DRD4 (0.54) | MAPTSMN1; SMN2GAAKDM4ELMNA | |
| SCHEMBL8555924 | 0.82 | MAPT (0.53) | MAPTGFERGAAKDM4ELMNA | |
| SCHEMBL8556657 | 0.75 | MEN1 (0.51) | KDM4EALDH1A1KMT2AMEN1POLB | |
| SCHEMBL8557359 | 0.73 | CXCR4 (0.43) | SMN1; SMN2GAAALDH1A1KMT2AHTT | |
| SCHEMBL7481150 | 0.73 | ALDH1A1 (0.41) | MAPTSMN1; SMN2GFERGAAKDM4E | |
| SCHEMBL8558421 | 0.73 | ALDH1A1 (0.55) | MAPTSMN1; SMN2KDM4ELMNAALDH1A1 | |
| SCHEMBL8556503 | 0.73 | SIGMAR1 (0.58) | LMNAALDH1A1KMT2APOLBHSD17B10 | |
| SCHEMBL6698408 | 0.71 | MAPT (0.50) | MAPTSMN1; SMN2GFERGAAKDM4E | |
| SCHEMBL8560517 | 0.71 | CYP2C19 (0.40) | MAPTSMN1; SMN2GAAKDM4ELMNA | |
| SCHEMBL8555169 | 0.71 | DRD2 (0.38) | ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883622-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1998-12-16 | — | — | EP | disclosed |
| WO-1997031923-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1997-09-04 | — | — | WO | disclosed |