Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550978 | 0.86 | MAPT (0.46) | ALDH1A1SMN1; SMN2KMT2AAKR1C3 | |
| SCHEMBL8547353 | 0.85 | PLAAT3 (0.43) | EPHX2ABCG2NPC1ALDH1A1RAB9A | |
| SCHEMBL8548995 | 0.84 | ALOX5 (0.42) | POLBNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL8550399 | 0.83 | ALDH1A1 (0.41) | POLBNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL8548352 | 0.82 | SMN1; SMN2 (0.42) | EPHX2ABCG2NPC1ALDH1A1RAB9A | |
| SCHEMBL8551274 | 0.82 | PLAAT3 (0.41) | POLBABCG2NPC1ALDH1A1RAB9A | |
| SCHEMBL8552707 | 0.81 | ALDH1A1 (0.52) | POLBNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL8551925 | 0.81 | GRIK1 (0.46) | NPC1ALDH1A1RAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL8152711 | 0.81 | POLB (0.40) | EPHX2POLBNPC1ALDH1A1RAB9A | |
| SCHEMBL8156192 | 0.79 | POLB (0.44) | POLBSMN1; SMN2KMT2AGRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |