Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.34 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.34 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.34 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551274 | 0.87 | PLAAT3 (0.41) | SMN1; SMN2ALDH1A1NPC1RAB9AAKR1C3 | |
| SCHEMBL8552707 | 0.87 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1NPC1RAB9AAKR1C3 | |
| SCHEMBL8551925 | 0.86 | GRIK1 (0.46) | SMN1; SMN2ALDH1A1NPC1RAB9AAKR1C3 | |
| SCHEMBL8550399 | 0.86 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1NPC1RAB9AAKR1C3 | |
| SCHEMBL8548995 | 0.84 | ALOX5 (0.42) | SMN1; SMN2ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL8550978 | 0.84 | MAPT (0.46) | SMN1; SMN2ALDH1A1AKR1C3LMNAPLAAT3 | |
| SCHEMBL8547353 | 0.82 | PLAAT3 (0.43) | SMN1; SMN2ALDH1A1NPC1RAB9AAKR1C3 | |
| SCHEMBL8593809 | 0.82 | FBP1 (0.40) | SMN1; SMN2ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL8556300 | 0.82 | EPHX2 (0.38) | SMN1; SMN2ALDH1A1NPC1RAB9AAKR1C3 | |
| SCHEMBL8547323 | 0.81 | MAPT (0.42) | SMN1; SMN2ALDH1A1NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |