Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.39 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.39 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.39 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551274 | 0.88 | PLAAT3 (0.41) | ALDH1A1NPC1RAB9ASMN1; SMN2PLAAT3 | |
| SCHEMBL8552707 | 0.88 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9ASMN1; SMN2PLAAT3 | |
| SCHEMBL8550579 | 0.87 | NPC1 (0.35) | ALDH1A1NPC1RAB9ASMN1; SMN2PLAAT3 | |
| SCHEMBL8551925 | 0.87 | GRIK1 (0.46) | ALDH1A1NPC1RAB9ASMN1; SMN2PLAAT3 | |
| SCHEMBL8554588 | 0.86 | TRPA1 (0.38) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8547353 | 0.86 | PLAAT3 (0.43) | ALDH1A1NPC1RAB9ASMN1; SMN2PLAAT3 | |
| SCHEMBL8548352 | 0.86 | SMN1; SMN2 (0.42) | ALDH1A1NPC1RAB9ASMN1; SMN2PLAAT3 | |
| SCHEMBL8550868 | 0.85 | AKR1C3 (0.43) | ALDH1A1NPC1RAB9ASMN1; SMN2PLAAT3 | |
| SCHEMBL8550978 | 0.85 | MAPT (0.46) | ALDH1A1SMN1; SMN2PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL8593809 | 0.84 | FBP1 (0.40) | ALDH1A1L3MBTL1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |