Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.67 |
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9861767 | 0.86 | CES1 (0.67) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL5158726 | 0.82 | CES1 (0.61) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL28445929 | 0.82 | CES1 (0.61) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL132067 | 0.80 | CES1 (0.58) | CES1CES2ALDH1A1TSHRDAO | |
| Benzene SCHEMBL27672585 | 0.80 | CES1 (1.00) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL33083 | 0.80 | CES1 (1.00) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL11183801 | 0.80 | CES1 (0.58) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL7907262 | 0.80 | CES1 (0.73) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL28741013 | 0.79 | CES1 (0.57) | CES1CES2ALDH1A1TSHRDAO | |
| Benzoic Acid SCHEMBL21747702 | 0.78 | TSHR (0.70) | CES1CES2ALDH1A1TSHRDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 314 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114085234-B | Process for preparing 1, 3-benzodioxole heterocyclic compounds | 联合疗法公司 | 2024-12-17 | — | — | CN | claimed |
| CN-117143005-A | Fluoro methyl bis-carbazolyl methane compound and synthesis method thereof | 宁波大学 | 2023-12-01 | — | — | CN | claimed |
| EP-3390407-B1 | METHODS FOR THE PREPARATION OF 1,3-BENZODIOXOLE HETEROCYCLIC COMPOUNDS | UNION THERAPEUTICS AS (DK) | 2023-10-11 | — | — | EP | claimed |
| US-20230073362-A1 | METHODS FOR THE PREPARATION OF 1,3-BENZODIOXOLE HETEROCYCLIC COMPOUNDS | UNION therapeutics A/S (DK) | 2023-03-09 | — | — | US | claimed |
| US-11370799-B2 | Methods for the preparation of 1,3-benzodioxole heterocyclic compounds | UNION therapeutics A/S (DK) | 2022-06-28 | — | — | US | claimed |
| US-20220162227-A1 | METHODS FOR THE PREPARATION OF 1,3-BENZODIOXOLE HETEROCYCLIC COMPOUNDS | UNION therapeutics A/S (DK) | 2022-05-26 | — | — | US | claimed |
| US-20200262842-A1 | METHODS FOR THE PREPARATION OF 1,3-BENZODIOXOLE HETEROCYCLIC COMPOUNDS | UNION therapeutics A/S (DK) | 2020-08-20 | — | — | US | claimed |
| CN-102775345-A | Preparation method of roflumilast and intermediates | TOPHARMAN SHANGHAI CO LTD | 2012-11-14 | — | — | CN | claimed |
| US-12630514-B2 | Process and intermediates for the preparation of pyroxasulfone | ADAMA AGAN LTD. (IL) | 2026-05-19 | — | — | US | disclosed |
| US-20260035383-A1 | METHODS FOR THE PREPARATION OF 1,3-BENZODIOXOLE HETEROCYCLIC COMPOUNDS | UNION THERAPEUTICS AS (DK) | 2026-02-05 | — | — | US | disclosed |
| US-12497382-B2 | GLP-1R modulating compounds | GILEAD SCIENCES, INC. (US) | 2025-12-16 | — | — | US | disclosed |
| WO-2025128933-A1 | GABA-A RECEPTOR POSITIVE ALLOSTERIC MODULATORS AND METHODS OF USE THEREOF | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2025-06-19 | — | — | WO | disclosed |
| CN-119874674-A | GLP-1R modulating compounds | 吉利德科学公司 | 2025-04-25 | — | — | CN | disclosed |
| US-12263171-B2 | 7-, 8-, and 10-substituted amino triazolo quinazoline derivatives as adenosine receptor antagonists, pharmaceutical compositions and their use | MERCK SHARP & DOHME LLC (US) | 2025-04-01 | — | — | US | disclosed |
| US-5986144-A | Triazole derivative, preparation process thereof and pharmaceutical comprising the same as an effective ingredient | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-11-16 | — | — | US | disclosed |
| US-5945438-A | ANTIMYCOTIC AGENT | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-08-31 | — | — | US | disclosed |
| EP-0780380-A1 | Triazole derivatives with antimycotic action and intermediates | SS PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |
| US-5081273-A | PROCESS FOR THE PREPARATION OF INSECTICIDALLY ACTIVE DIPHENYL ETHER COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-14 | — | — | US | disclosed |
| US-4942264-A | WITTIG REACTION FOLLOWED BY REDUCTION | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-07-17 | — | — | US | disclosed |
| EP-0298478-A2 | Method for the production of alpha-gluoroketones | CIBA-GEIGY AG (CH) | 1989-01-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200262842-A1 | METHODS FOR THE PREPARATION OF 1,3-BENZODIOXOLE HETEROCYCLIC COMPOUNDS | PDE4B, PDE4A, PDE4C | CES1 297/4885CES2 291/4885ALDH1A1 687/4885 |
| US-20230073362-A1 | METHODS FOR THE PREPARATION OF 1,3-BENZODIOXOLE HETEROCYCLIC COMPOUNDS | PDE4B, PDE4A, PDE3B | CES1 223/4885CES2 190/4885ALDH1A1 618/4885 |
| US-12630514-B2 | Process and intermediates for the preparation of pyroxasulfone | MRPS23, CYP2E1, CYP2S1 | CES1 1130/4885CES2 2480/4885ALDH1A1 1705/4885 |
| US-12263171-B2 | 7-, 8-, and 10-substituted amino triazolo quinazoline derivatives as adenosine receptor antagonists, pharmaceutical compositions and their use | ADORA2A, ADORA2B, ADORA3 | CES1 2056/4885CES2 2456/4885ALDH1A1 1156/4885 |
| US-20220162227-A1 | METHODS FOR THE PREPARATION OF 1,3-BENZODIOXOLE HETEROCYCLIC COMPOUNDS | PDE4B, PDE4A, PDE4C | CES1 286/4885CES2 216/4885ALDH1A1 748/4885 |
| US-20260035383-A1 | METHODS FOR THE PREPARATION OF 1,3-BENZODIOXOLE HETEROCYCLIC COMPOUNDS | NOX4, PDE3B, CBR1 | CES1 258/4885CES2 117/4885ALDH1A1 59/4885 |
| US-12497382-B2 | GLP-1R modulating compounds | GLP1R, GIPR, GPR119 | CES1 877/4885CES2 3464/4885ALDH1A1 3556/4885 |
| US-11370799-B2 | Methods for the preparation of 1,3-benzodioxole heterocyclic compounds | PDE4B, PDE4A, PDE4C | CES1 297/4885CES2 291/4885ALDH1A1 687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.