Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668935 | 0.83 | LMNA (0.55) | ALDH1A1LMNAKMT2AMEN1CYP3A4 | |
| SCHEMBL8556503 | 0.79 | SIGMAR1 (0.58) | ALDH1A1LMNAKMT2ACYP3A4DRD2 | |
| SCHEMBL2579539 | 0.78 | LMNA (0.72) | ALDH1A1LMNAKMT2AMEN1CYP3A4 | |
| SCHEMBL8555562 | 0.76 | DRD4 (0.54) | ALDH1A1LMNAKMT2AGAADRD2 | |
| SCHEMBL6991083 | 0.72 | ALDH1A1 (0.51) | ALDH1A1LMNAKMT2AMEN1CYP3A4 | |
| SCHEMBL613704 | 0.71 | LTA4H (0.77) | ALDH1A1LMNAKMT2AMEN1CYP3A4 | |
| SCHEMBL11036914 | 0.71 | LTA4H (0.77) | ALDH1A1LMNAKMT2AMEN1CYP3A4 | |
| SCHEMBL16226425 | 0.71 | SMN1; SMN2 (0.62) | ALDH1A1LMNAKMT2AMEN1CYP3A4 | |
| SCHEMBL16226424 | 0.71 | SMN1; SMN2 (0.62) | ALDH1A1LMNAKMT2AMEN1CYP3A4 | |
| SCHEMBL7261524 | 0.70 | LMNA (0.62) | ALDH1A1LMNAKMT2AMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883622-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1998-12-16 | — | — | EP | claimed |
| WO-1997031923-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1997-09-04 | — | — | WO | claimed |
| EP-0883606-A1 | PROCESS FOR SCAVENGING THIOLS | APOTEX INC. (CA) | 1998-12-16 | — | — | EP | disclosed |
| WO-1997031893-A1 | PROCESS FOR SCAVENGING THIOLS | APOTEX INC. (CA) | 1997-09-04 | — | — | WO | disclosed |