Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559969 | 0.89 | PPARD (0.49) | MAPTL3MBTL1KDM4EPPARDPPARA | |
| SCHEMBL8559981 | 0.84 | PARP10 (0.39) | ALDH1A1KDM4ENPC1MEN1KMT2A | |
| SCHEMBL8835183 | 0.80 | PARP10 (0.50) | ALDH1A1KDM4ENPC1RAB9AHPGD | |
| SCHEMBL8560309 | 0.75 | KCNH2 (0.39) | MAPTALDH1A1KDM4EPPARANPC1 | |
| SCHEMBL8557729 | 0.74 | PDE10A (0.43) | MAPTPKMKDM4ENPC1RAB9A | |
| SCHEMBL8834199 | 0.73 | GPBAR1 (0.55) | ALOX5 | |
| SCHEMBL8649482 | 0.72 | MAPT (0.47) | MAPTL3MBTL1ALDH1A1PKMPPP1CA | |
| SCHEMBL8559028 | 0.72 | PDE10A (0.45) | MAPTNPC1RAB9AMEN1LMNA | |
| SCHEMBL8557214 | 0.72 | ADORA3 (0.47) | MAPTL3MBTL1ALDH1A1PKMPPP1CA | |
| SCHEMBL8557960 | 0.70 | GRM5 (0.41) | MAPTALDH1A1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | disclosed |