Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562004 | 0.85 | ALOX5 (0.46) | KMT2AMEN1HTTTHRBALDH1A1 | |
| SCHEMBL18689633 | 0.84 | KMT2A (0.54) | KMT2AMEN1HTTTHRBALDH1A1 | |
| SCHEMBL8558770 | 0.84 | ALOX5 (0.48) | KMT2AMEN1HTTTHRBGAA | |
| SCHEMBL8561075 | 0.84 | ALOX5 (0.48) | KMT2AMEN1HTTTHRBALDH1A1 | |
| SCHEMBL8561459 | 0.80 | PTGES (0.43) | KMT2AMEN1HTTTHRBALDH1A1 | |
| SCHEMBL1564355 | 0.80 | ALDH1A1 (0.64) | KMT2AMEN1HTTALDH1A1GAA | |
| SCHEMBL31493092 | 0.78 | ALDH1A1 (0.52) | KMT2AMEN1HTTALDH1A1GAA | |
| SCHEMBL11464975 | 0.78 | NUDT1 (0.67) | KMT2AMEN1HTTALDH1A1GAA | |
| SCHEMBL3545118 | 0.78 | ALKBH1 (0.43) | KMT2AMEN1HTTGAAADORA3 | |
| SCHEMBL12157689 | 0.78 | ALDH1A1 (0.51) | KMT2AMEN1HTTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250313554-A1 | PTPN2 INHIBITORS | MONDEGO BIO, LDA. (PT) | 2025-10-09 | — | — | US | disclosed |
| EP-4522594-A1 | PTPN2 INHIBITORS | Ness Therapeutics, Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023220572-A1 | PTPN2 INHIBITORS | NESS THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023220572-A1 | PTPN2 INHIBITORS | NESS THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| US-5726128-A | Benzyloxypyrimidine derivative, processes for producing the same and herbicidal composition | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-03-10 | — | — | US | disclosed |
| EP-0707001-A1 | Benzyloxypyrimidine derivative, processes for producing the same and herbicidal composition | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1996-04-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250313554-A1 | PTPN2 INHIBITORS | PTPN2, PTPN1, PTPRJ | KMT2A 1912/4885MEN1 3303/4885HTT 1504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.