Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557424 | 0.84 | KMT2A (0.61) | ALOX5PTGESNUDT1ADORA3ADORA1 | |
| SCHEMBL8562004 | 0.84 | ALOX5 (0.46) | ALOX5PTGESNUDT1ADORA3ADORA1 | |
| SCHEMBL8558770 | 0.82 | ALOX5 (0.48) | ALOX5PTGESNUDT1ADORA3ADORA1 | |
| SCHEMBL8561459 | 0.79 | PTGES (0.43) | ALOX5PTGESNUDT1ADORA3ADORA1 | |
| SCHEMBL7706826 | 0.78 | ALDH1A1 (0.47) | ALOX5PTGESNUDT1HTTALDH1A1 | |
| SCHEMBL8773216 | 0.78 | MAOB (0.51) | ALOX5PTGESNUDT1HTTALDH1A1 | |
| SCHEMBL3545118 | 0.77 | ALKBH1 (0.43) | ALOX5PTGESNUDT1ADORA3ADORA1 | |
| SCHEMBL8562901 | 0.74 | SMN1; SMN2 (0.45) | ALOX5PTGESNUDT1ADORA3ADORA1 | |
| SCHEMBL17594829 | 0.74 | MAOB (0.58) | ALOX5KMT2AMEN1MAOBGAA | |
| SCHEMBL3875774 | 0.72 | LMNA (0.46) | ALDH1A1MAPK14GAALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726128-A | Benzyloxypyrimidine derivative, processes for producing the same and herbicidal composition | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-03-10 | — | — | US | disclosed |
| EP-0707001-A1 | Benzyloxypyrimidine derivative, processes for producing the same and herbicidal composition | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1996-04-17 | — | — | EP | disclosed |