Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18931737 | 0.87 | ADORA3 (0.43) | ALOX5PTGESADORA3ADORA1PPARG | |
| SCHEMBL3315512 | 0.85 | ADORA3 (0.49) | ADORA3ADORA1KMT2AMEN1LMNA | |
| SCHEMBL8562004 | 0.84 | ALOX5 (0.46) | ALOX5PTGESADORA3ADORA1PPARG | |
| SCHEMBL8557424 | 0.84 | KMT2A (0.61) | ALOX5PTGESADORA3ADORA1PPARG | |
| SCHEMBL8561075 | 0.82 | ALOX5 (0.48) | ALOX5PTGESADORA3ADORA1PPARG | |
| SCHEMBL603696 | 0.80 | NUDT1 (0.48) | ALOX5PTGESNUDT1HTTGRM5 | |
| SCHEMBL8561459 | 0.79 | PTGES (0.43) | ALOX5PTGESADORA3ADORA1PPARG | |
| SCHEMBL8384805 | 0.78 | PIN1 (0.47) | ALOX5PTGESNUDT1GRM5PKM | |
| SCHEMBL25592214 | 0.78 | TSHR (0.48) | PPARGKMT2AMEN1LMNATSHR | |
| SCHEMBL2387324 | 0.78 | ADORA3 (0.48) | ADORA3ADORA1KMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164965-A | Pyrimidine-triazole-fluorine substituted phenyl cyclopropylamine derivative and application thereof | 郑州大学 | 2024-06-11 | — | — | CN | disclosed |
| US-5726128-A | Benzyloxypyrimidine derivative, processes for producing the same and herbicidal composition | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-03-10 | — | — | US | disclosed |
| EP-0707001-A1 | Benzyloxypyrimidine derivative, processes for producing the same and herbicidal composition | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1996-04-17 | — | — | EP | disclosed |