Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21359083 | 0.84 | MAPT (0.44) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL17790348 | 0.75 | NPSR1 (0.41) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL9464475 | 0.75 | NPSR1 (0.44) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL8488793 | 0.72 | GRIN1 (0.40) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL3066016 | 0.72 | MAPT (0.47) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL13345042 | 0.71 | NPSR1 (0.44) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL1371755 | 0.71 | NPSR1 (0.44) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL692131 | 0.71 | ALDH1A1 (0.47) | MAPTKMT2ALMNAALDH1A1L3MBTL1 | |
| SCHEMBL11348441 | 0.71 | TRPV4 (0.41) | ALDH1A1L3MBTL1GAATP53TRPV4 | |
| SCHEMBL6523291 | 0.71 | L3MBTL1 (0.46) | LMNAALDH1A1L3MBTL1TRPV4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767283-A | CHEMICAL INTERMEDIATE FOR 7-N-ORGANOSULFONYL-1H-INDOLE DERIVATIVE ANTITUMOR AGENTS; NONTOXIC | EISAI CO., LTD. (JP) | 1998-06-16 | — | — | US | disclosed |
| US-5721246-A | ANTITUMOR AGENTS; LOW TOXICITY | EISAI CO., LTD. (JP) | 1998-02-24 | — | — | US | disclosed |