Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 2/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7488303 | 0.80 | KDM1A (0.54) | NCF1SLC22A12LOXL2HTR1AADRA1D | |
| SCHEMBL4371190 | 0.80 | MEN1 (0.43) | NCF1SLC22A12LOXL2HTR1AADRA1D | |
| SCHEMBL27306674 | 0.80 | NCF1 (0.46) | NCF1SLC22A12LOXL2HTR1AADRA1D | |
| SCHEMBL8565482 | 0.75 | ADRB2 (0.42) | NCF1SLC22A12ALDH1A1MEN1KMT2A | |
| SCHEMBL8563075 | 0.74 | MAPT (0.52) | MAPTKDM4ECYP1A2NPC1RAB9A | |
| SCHEMBL13239525 | 0.74 | HPGD (0.53) | SLC22A12MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL8564352 | 0.72 | IFNAR1 (0.47) | MAPTCYP1A2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL7488299 | 0.71 | NCF1 (0.56) | NCF1SLC22A12LOXL2HTR1AADRA1D | |
| SCHEMBL21082253 | 0.71 | NCF1 (0.50) | NCF1SLC22A12LOXL2HTR1AADRA1D | |
| SCHEMBL7053633 | 0.71 | NCF1 (0.50) | NCF1SLC22A12LOXL2HTR1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814646-A | TREATING THE PROGRESSION OF ALZHEIMER'S DISEASE, BRAIN DISORDERS | ELI LILLY AND COMPANY (US) | 1998-09-29 | — | — | US | disclosed |