Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.40 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | DUSP26 | Q9BV47 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561447 | 0.92 | FBP1 (0.45) | PGRFBP1MAPTALDH1A1LMNA | |
| SCHEMBL8559341 | 0.89 | MAPT (0.44) | PGRFBP1MAPTALDH1A1LMNA | |
| SCHEMBL8553814 | 0.88 | MAPT (0.45) | PGRFBP1MAPTALDH1A1LMNA | |
| SCHEMBL8556141 | 0.85 | KAT6A (0.46) | PGRFBP1MAPTALDH1A1LMNA | |
| SCHEMBL8560337 | 0.84 | MAPT (0.50) | PGRFBP1MAPTALDH1A1LMNA | |
| SCHEMBL8560000 | 0.84 | KMO (0.47) | PGRMAPTALDH1A1LMNARXRA | |
| SCHEMBL8556146 | 0.84 | PGR (0.50) | PGRFBP1MAPTALDH1A1LMNA | |
| SCHEMBL8556039 | 0.84 | MAPT (0.44) | PGRFBP1MAPTALDH1A1LMNA | |
| SCHEMBL8556712 | 0.83 | MAPT (0.42) | PGRMAPTALDH1A1LMNAKDM4E | |
| SCHEMBL8559381 | 0.83 | ALDH1A1 (0.49) | PGRFBP1MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |