Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL981222 | 0.80 | SLC6A2 (0.41) | ARPPARDSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1092065 | 0.80 | PPARG (0.32) | PPARGPPARAARPPARD | |
| SCHEMBL8567630 | 0.77 | SLC6A4 (0.39) | PPARGATMPPARAARL3MBTL1 | |
| SCHEMBL10961574 | 0.74 | GABRA1 (0.46) | PPARGATMPPARAL3MBTL1PPARD | |
| SCHEMBL981200 | 0.73 | LTB4R (0.39) | PPARGPPARAARPPARDKDM4E | |
| SCHEMBL21523926 | 0.72 | ATM (0.42) | PPARGCYP2D6ATMPPARAL3MBTL1 | |
| SCHEMBL983437 | 0.72 | THRA (0.40) | CYP2D6PPARA | |
| SCHEMBL983871 | 0.71 | THRA (0.45) | PPARGPPARA | |
| SCHEMBL979986 | 0.70 | L3MBTL1 (0.43) | ATMARL3MBTL1MAPTTSHR | |
| SCHEMBL8560257 | 0.70 | RAB9A (0.47) | PPARGPPARAL3MBTL1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814646-A | TREATING THE PROGRESSION OF ALZHEIMER'S DISEASE, BRAIN DISORDERS | ELI LILLY AND COMPANY (US) | 1998-09-29 | — | — | US | disclosed |