SCHEMBL8563842

SCHEMBL8563842

O=CNCCC(=O)NCCO

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 5/20 0.44
ALDH1A1 P00352 4/20 0.44
NAAA Q02083 1/20 0.42
MEN1 O00255 2/20 0.41
BLM P54132 2/20 0.41
KMT2A Q03164 2/20 0.41
TRPV1 Q8NER1 2/20 0.41
TRPM8 Q7Z2W7 1/20 0.41
FAAH O00519 1/20 0.41
KCNK3 O14649 1/20 0.41
CNR2 P34972 1/20 0.41
HPGD P15428 2/20 0.40
MAPT P10636 1/20 0.40
ALOX12 P18054 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21505016 0.81 CNR1 (0.46) CNR1ALDH1A1NAAAMEN1BLM
SCHEMBL10892758 0.81 HDAC3 (0.43) ALDH1A1NAAAMEN1KMT2A
SCHEMBL18878750 0.81 ADH1B (0.56) CNR1NAAAMEN1KMT2AFAAH
SCHEMBL21300811 0.81 SLC6A5 (0.39) ALDH1A1NAAAMEN1KMT2A
SCHEMBL13227429 0.80 LMNA (0.50) CNR1ALDH1A1MEN1BLMKMT2A
SCHEMBL19752648 0.79 ALDH1A1 (0.41) ALDH1A1NAAAMEN1KMT2A
SCHEMBL6025053 0.78 FAAH (0.47) NAAAMEN1KMT2AFAAH
SCHEMBL2186533 0.78 GAA (0.53) CNR1ALDH1A1NAAAMEN1BLM
SCHEMBL18878659 0.78 PRMT1 (0.53) MEN1KMT2AMAPT
SCHEMBL16710251 0.77 FAAH (0.43) ALDH1A1MEN1BLMKMT2AFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100179075-A1 PARTICLES FOR USE IN SUPPORTED NUCLEIC ACID LIGATION AND DETECTION SEQUENCING Life Technologies Corporation (US) 2010-07-15 US disclosed
EP-0863881-A1 BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-09-16 EP disclosed
WO-1997010219-A1 BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-03-20 WO disclosed