Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 3/20 | 0.56 |
| ▸ | DRD4 | P21917 | 3/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6165224 | 0.90 | OPRM1 (0.52) | CHRM3DRD4FAAHOPRL1OPRM1 | |
| SCHEMBL6168606 | 0.88 | OPRL1 (0.52) | CHRM3DRD4DRD3DRD2OPRL1 | |
| SCHEMBL29445321 | 0.88 | OPRL1 (0.52) | CHRM3DRD4DRD3DRD2OPRL1 | |
| SCHEMBL8564439 | 0.86 | CHRM2 (0.55) | CHRM3DRD4DRD3DRD2OPRL1 | |
| SCHEMBL8569557 | 0.85 | CHRM2 (0.54) | CHRM3DRD4DRD3DRD2OPRL1 | |
| SCHEMBL8570520 | 0.85 | OPRL1 (0.45) | CHRM3DRD4DRD3DRD2OPRL1 | |
| SCHEMBL8562946 | 0.85 | CHRM3 (0.54) | CHRM3OPRL1OPRM1CHRM2 | |
| SCHEMBL8565541 | 0.85 | CHRM2 (0.54) | CHRM3OPRL1CHRM2 | |
| SCHEMBL8571871 | 0.85 | CHRM3 (0.54) | CHRM3DRD3DRD2OPRL1OPRM1 | |
| SCHEMBL6164748 | 0.85 | OPRL1 (0.44) | CHRM3DRD2OPRL1OPRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626373-B1 | Quinazolinone derivatives | SUMITOMO PHARMA (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5556860-A | ANTIISCHEMIC AGENTS, BRAIN DISORDERS AND BLOOD METAL CONCENTRATIONS AND KIDNEY DISEASE | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0626373-A1 | Quinazolinone derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |