Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ASPH | Q12797 | 1/20 | 0.37 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | F12 | P00748 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561727 | 0.84 | KMT2A (0.42) | KDM4ECES2CES1MEN1KMT2A | |
| SCHEMBL8570524 | 0.80 | MAPT (0.42) | KDM4EMAPK1MEN1KMT2AMAPT | |
| SCHEMBL8560442 | 0.79 | KDM4E (0.45) | KDM4EASPHKDM8MEN1KMT2A | |
| SCHEMBL8562881 | 0.76 | MAPK1 (0.37) | MAPK1CES2CES1F12MAPK14 | |
| SCHEMBL8567497 | 0.75 | ALDH1A1 (0.42) | KDM4EASPHKDM8MEN1KMT2A | |
| SCHEMBL8563396 | 0.75 | CES2 (0.39) | KDM4EASPHKDM8CES2CES1 | |
| SCHEMBL8563829 | 0.74 | MAPK1 (0.37) | KDM4EASPHKDM8MAPK1KMT2A | |
| SCHEMBL8561698 | 0.72 | NSD2 (0.50) | MAPK1MEN1KMT2AHTTLMNA | |
| SCHEMBL8560654 | 0.72 | RAB9A (0.52) | MAPK1MEN1KMT2AMAPTHTT | |
| SCHEMBL8565828 | 0.71 | MAPT (0.39) | KDM4EASPHKDM8MAPK1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |