Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | CASP4 | P49662 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | CASP9 | P55211 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SNCA | P37840 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8572953 | 0.95 | CASP1 (0.46) | CASP1CASP3CASP4CASP7CASP9 | |
| SCHEMBL8573630 | 0.88 | ALDH1A1 (0.40) | MAPTALDH1A1HTT | |
| SCHEMBL8576804 | 0.87 | ALDH1A1 (0.38) | ACHEMAPTALDH1A1LMNA | |
| SCHEMBL8578867 | 0.84 | CTRB1 (0.36) | MAPTALDH1A1HPGDLMNA | |
| SCHEMBL8574470 | 0.83 | CASP1 (0.41) | CASP1CASP3CASP4CASP7CASP9 | |
| SCHEMBL8574464 | 0.83 | ACHE (0.36) | ACHEMAPTALDH1A1 | |
| SCHEMBL8575403 | 0.83 | ALDH1A1 (0.41) | MAPTALDH1A1HTTLMNA | |
| SCHEMBL8578845 | 0.83 | CASP1 (0.41) | CASP1CASP3CASP4CASP7CASP9 | |
| SCHEMBL8577585 | 0.82 | MAPT (0.37) | ACHEMAPTALDH1A1LMNA | |
| SCHEMBL8573201 | 0.81 | POLB (0.37) | ACHEMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710152-A | ANTIDIABETIC, ANTILIPEMIC, AND HYPOGLYCEMIC AGENTS; DIETETICS | SS PHARMACEUTICAL CO., LTD. (JP) | 1998-01-20 | — | — | US | disclosed |