Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8573630 | 0.95 | ALDH1A1 (0.40) | ALDH1A1ALDH2ALDH3A1MAPTTHRB | |
| SCHEMBL8574464 | 0.91 | ACHE (0.36) | ALDH1A1ALDH2ALDH3A1MAPTTHRB | |
| SCHEMBL8577585 | 0.90 | MAPT (0.37) | ALDH1A1MAPTTHRBPOLBTP53 | |
| SCHEMBL8573201 | 0.90 | POLB (0.37) | ALDH1A1ALDH2ALDH3A1MAPTTHRB | |
| SCHEMBL8572909 | 0.88 | ADRA1D (0.35) | ALDH1A1MAPTTHRBPOLBGAA | |
| SCHEMBL8579010 | 0.88 | POLB (0.34) | ALDH1A1MAPTTHRBPOLBTP53 | |
| SCHEMBL8572953 | 0.88 | CASP1 (0.46) | ALDH1A1MAPTHTTLMNA | |
| SCHEMBL8575074 | 0.86 | TSHR (0.35) | ALDH1A1POLBGAALMNA | |
| SCHEMBL8576804 | 0.85 | ALDH1A1 (0.38) | ALDH1A1MAPTTHRBPOLBTP53 | |
| SCHEMBL8578867 | 0.83 | CTRB1 (0.36) | ALDH1A1MAPTPOLBTP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710152-A | ANTIDIABETIC, ANTILIPEMIC, AND HYPOGLYCEMIC AGENTS; DIETETICS | SS PHARMACEUTICAL CO., LTD. (JP) | 1998-01-20 | — | — | US | disclosed |