Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.38 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8577585 | 0.95 | MAPT (0.37) | ALDH1A1MAPTKMT2AL3MBTL1TP53 | |
| SCHEMBL8573630 | 0.91 | ALDH1A1 (0.40) | ALDH1A1MAPTKMT2ATP53POLB | |
| SCHEMBL8578867 | 0.87 | CTRB1 (0.36) | ALDH1A1MAPTKMT2AL3MBTL1TP53 | |
| SCHEMBL8574473 | 0.87 | CASP1 (0.44) | ALDH1A1MAPTLMNAACHE | |
| SCHEMBL8575403 | 0.85 | ALDH1A1 (0.41) | ALDH1A1MAPTKMT2ATP53POLB | |
| SCHEMBL8579010 | 0.85 | POLB (0.34) | ALDH1A1MAPTL3MBTL1TP53POLB | |
| SCHEMBL8574464 | 0.85 | ACHE (0.36) | ALDH1A1MAPTL3MBTL1TP53POLB | |
| SCHEMBL8573201 | 0.84 | POLB (0.37) | ALDH1A1MAPTTP53POLBGAA | |
| SCHEMBL8576883 | 0.83 | XIAP (0.36) | ALDH1A1MAPTGAATHRB | |
| SCHEMBL8572909 | 0.83 | ADRA1D (0.35) | ALDH1A1MAPTPOLBKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710152-A | ANTIDIABETIC, ANTILIPEMIC, AND HYPOGLYCEMIC AGENTS; DIETETICS | SS PHARMACEUTICAL CO., LTD. (JP) | 1998-01-20 | — | — | US | disclosed |