Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CXCR5 | P32302 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845267 | 1.00 | GHSR (0.42) | GHSRCA1CA2ACHEALDH1A1 | |
| SCHEMBL8845103 | 0.89 | GHSR (0.41) | GHSRALDH1A1CYP3A4TSHRCXCR5 | |
| SCHEMBL8845255 | 0.89 | CTSV (0.38) | GHSRALDH1A1CTSLMEN1POLB | |
| SCHEMBL8567143 | 0.87 | CA1 (0.39) | GHSRCA1CA2ACHEALDH1A1 | |
| SCHEMBL8575729 | 0.87 | CA1 (0.39) | GHSRCA1CA2ACHEALDH1A1 | |
| SCHEMBL8844917 | 0.87 | GHSR (0.35) | GHSRCA1CA2ACHEALDH1A1 | |
| SCHEMBL8844903 | 0.87 | CTSS (0.38) | GHSRCA1CA2ACHEALDH1A1 | |
| SCHEMBL8581093 | 0.86 | GHSR (0.40) | GHSRCA1CA2ACHESYK | |
| SCHEMBL8845595 | 0.82 | GHSR (0.39) | GHSRCA1CA2ACHESYK | |
| SCHEMBL8844932 | 0.82 | PRKCZ (0.42) | GHSRCA1CA2ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5644024-A | MIMICS OF PEPTIDE DOMAINS, SEQUENCE DETERMINATION, DRUGS | HOFFMANN-LA ROCHE INC. (US) | 1997-07-01 | — | — | US | disclosed |