Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.41 |
| ▸ | CXCR5 | P32302 | 12/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.34 |
| ▸ | RHOA | P61586 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845155 | 0.89 | GHSR (0.42) | GHSRCXCR5CYP3A4ALDH1A1TSHR | |
| SCHEMBL8845267 | 0.89 | GHSR (0.42) | GHSRCXCR5CYP3A4ALDH1A1TSHR | |
| SCHEMBL8563393 | 0.87 | CYP3A4 (0.38) | GHSRCXCR5CYP3A4ADRB2ADRB1 | |
| SCHEMBL8573147 | 0.87 | CYP3A4 (0.37) | GHSRCXCR5CYP3A4ADRB2ADRB1 | |
| SCHEMBL8579256 | 0.81 | GHSR (0.44) | GHSRCXCR5 | |
| SCHEMBL8583595 | 0.81 | GHSR (0.44) | GHSRCXCR5 | |
| SCHEMBL8845255 | 0.78 | CTSV (0.38) | GHSRALDH1A1 | |
| SCHEMBL8580646 | 0.78 | GHSR (0.42) | GHSRCXCR5ALDH1A1 | |
| SCHEMBL8844917 | 0.77 | GHSR (0.35) | GHSRCYP3A4ALDH1A1TSHR | |
| SCHEMBL8581093 | 0.77 | GHSR (0.40) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5644024-A | MIMICS OF PEPTIDE DOMAINS, SEQUENCE DETERMINATION, DRUGS | HOFFMANN-LA ROCHE INC. (US) | 1997-07-01 | — | — | US | disclosed |