Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8709022 | 0.80 | FABP4 (0.34) | GAAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL8584346 | 0.78 | KMT2A (0.37) | GAAKDM4EMAPTKMT2AMEN1 | |
| SCHEMBL8581833 | 0.73 | GAA (0.33) | GAAKDM4EMAPTKMT2AMEN1 | |
| SCHEMBL8933559 | 0.69 | IGF1R (0.45) | MAPTKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8537294 | 0.68 | IGF1R (0.38) | GAAKDM4EMAPTKMT2AMEN1 | |
| SCHEMBL8307820 | 0.66 | DYRK1A (0.61) | GAAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL8933462 | 0.66 | FABP4 (0.47) | GAAKDM4EMAPTKMT2AMEN1 | |
| SCHEMBL8310606 | 0.65 | MAPT (0.56) | GAAKDM4EMAPTKMT2AMEN1 | |
| SCHEMBL8583284 | 0.61 | PTGS2 (0.31) | GAAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL8709018 | 0.60 | KMT2A (0.35) | GAAKDM4EMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731336-A | USING ARYL-SUBSTITUTED RHODAMINES | ELI LILLY AND COMPANY (US) | 1998-03-24 | — | — | US | disclosed |