Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Tetramethylammonium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.80 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.80 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetramethylammonium Ion SCHEMBL845827 | 1.00 | — | — | |
| Tetramethylammonium Ion SCHEMBL5684461 | 1.00 | — | — | |
| Tetramethylammonium Ion SCHEMBL15205926 | 1.00 | CHRNB2 (0.80) | CHRNB2CHRNA7CHRNA4 | |
| Tetramethylammonium Ion SCHEMBL28549788 | 1.00 | CHRNB2 (0.80) | CHRNB2CHRNA7CHRNA4 | |
| Tetramethylammonium Ion SCHEMBL781770 | 1.00 | CHRNB2 (0.80) | CHRNB2CHRNA7CHRNA4 | |
| Tetramethylammonium Ion SCHEMBL9547013 | 1.00 | CHRNB2 (0.80) | CHRNB2CHRNA7CHRNA4 | |
| Tetramethylammonium Ion SCHEMBL7028672 | 1.00 | — | — | |
| Tetramethylammonium Ion SCHEMBL7166906 | 0.91 | CHRNB2 (0.67) | CHRNB2CHRNA7CHRNA4 | |
| Tetramethylammonium Ion SCHEMBL9114017 | 0.91 | — | — | |
| Tetramethylammonium Ion SCHEMBL3199241 | 0.91 | CHRNB2 (0.67) | CHRNB2CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106029046-B | Dental composition and application thereof | 3M创新有限公司 | 2019-04-05 | — | — | CN | disclosed |
| CN-102985052-B | Dental composition, assembly box set and application thereof | 3M创新有限公司 | 2016-10-19 | — | — | CN | disclosed |
| CN-106029046-A | Dental composition and use thereof | 3M创新有限公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-106029044-A | Adhesive bonding composition and use thereof | 3M创新有限公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-106029045-A | Dental composition and use thereof | 3M创新有限公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-101808981-B | Methacrylate based monomers containing a urethane linkage, process for production and use thereof | 3M INNOVATIVE PROPERTIES CO | 2014-07-30 | — | — | CN | disclosed |
| CN-102985052-A | Dental composition, kit of parts and use thereof | 3M INNOVATIVE PROPERTIES CO | 2013-03-20 | — | — | CN | disclosed |
| CN-101610749-B | Dental filler and methods | 3M INNOVATIVE PROPERTIES CO | 2013-01-02 | — | — | CN | disclosed |
| CN-101018818-B | Dental compositions conataining carbosilane polymers | 3M INNOVATIVE PROPERTIES CO | 2012-11-14 | — | — | CN | disclosed |
| CN-1997334-B | Dental compositions containing carbosilane monomers | 3M INNOVATIVE PROPERTIES CO | 2012-03-21 | — | — | CN | disclosed |
| CN-101808981-A | Methacrylate based monomers containing a urethane linkage, process for production and use thereof | 3M INNOVATIVE PROPERTIES CO | 2010-08-18 | — | — | CN | disclosed |
| CN-101610749-A | Dental filler and method | 3M INNOVATIVE PROPERTIES CO (US) | 2009-12-23 | — | — | CN | disclosed |
| CN-100415198-C | Hardenable self-supporting structures and methods | 3M INNOVATIVE PROPERTIES CO (US) | 2008-09-03 | — | — | CN | disclosed |
| CN-101018818-A | Dental compositions conataining carbosilane polymers | 3M INNOVATIVE PROPERTIES CO (US) | 2007-08-15 | — | — | CN | disclosed |
| CN-1997334-A | Dental compositions containing carbosilane monomers | 3M INNOVATIVE PROPERTIES CO (US) | 2007-07-11 | — | — | CN | disclosed |
| CN-1541084-A | Hardenable self-supporting structures and methods | 3M | 2004-10-27 | — | — | CN | disclosed |
| US-5717057-A | INHIBITING DISCOLORATION BY CONDENSATION POLYMERIZING IN PRESENSE OF POLYMERIZATION CATALYST DISSOLVING OR DISPERSING IN STARTING MATERIAL A CARBONIC ACID DIESTER, A MONOHYDROXY COMPOUND OR AN AQUEOUS SOLUTION OF MONOHYDROXY COMPOUND | GENERAL ELECTRIC COMPANY (US) | 1998-02-10 | — | — | US | disclosed |