SCHEMBL859433

SCHEMBL859433

Sc1nnnn1-c1cccc2ccccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 13/20 0.49
ADRB2 P07550 1/20 0.49
HSD17B10 Q99714 3/20 0.47
HPGD P15428 5/20 0.45
SMN1; SMN2 Q16637 4/20 0.45
MAPT P10636 4/20 0.45
CA12 O43570 1/20 0.43
CA9 Q16790 1/20 0.43
NOTUM Q6P988 1/20 0.42
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
HTT P42858 3/20 0.42
TSHR P16473 3/20 0.42
NPC1 O15118 2/20 0.42
LMNA P02545 2/20 0.42
GLA P06280 1/20 0.42
PKM P14618 1/20 0.42
RAB9A P51151 1/20 0.42
MAPK1 P28482 1/20 0.41
POLB P06746 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11216097 0.84 ALDH1A1 (0.41) ALDH1A1ADRB2HSD17B10HPGDSMN1; SMN2
SCHEMBL15104652 0.79 ALDH1A1 (0.49) ALDH1A1ADRB2HSD17B10HPGDSMN1; SMN2
SCHEMBL10466989 0.79 ALDH1A1 (0.49) ALDH1A1ADRB2HSD17B10HPGDSMN1; SMN2
SCHEMBL860219 0.79 ALDH1A1 (0.50) ALDH1A1ADRB2HSD17B10HPGDSMN1; SMN2
SCHEMBL30353932 0.79 ALDH1A1 (0.49) ALDH1A1ADRB2HSD17B10HPGDSMN1; SMN2
SCHEMBL10629073 0.77 ALDH1A1 (0.64) ALDH1A1ADRB2HSD17B10HPGDSMN1; SMN2
SCHEMBL5551521 0.76 ALDH1A1 (0.46) ALDH1A1ADRB2HSD17B10HPGDSMN1; SMN2
SCHEMBL14112954 0.75 KCNN4 (0.54)
SCHEMBL2210006 0.75 KCNMA1 (0.50) ALDH1A1HSD17B10HPGDMAPTHTT
SCHEMBL3294567 0.75 KCNN4 (0.45) ALDH1A1HPGDSMN1; SMN2MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4063950-A DEVELOPMENT INHIBITOR RELEASING COMPOUND, SILVER HALIDE EMULSIONS ON KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1977-12-20 US claimed
US-4049455-A DEVELOPMENT INHIBITOR RELEASING COMPOUND KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1977-09-20 US claimed
US-4010035-A DEVELOPMENT INHIBITOR RELEASING COMPOUND, HARDENER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1977-03-01 US claimed
US-3961959-A DEVELOPMENT RELEASING INHIBITOR KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1976-06-08 US claimed
US-3938996-A Process for developing light-sensitive silver halide photographic materials KONISHIROKU PHOTO INDUSTRY CO. LTD. (JA) 1976-02-17 US claimed
US-12584046-B2 Gas generating agent, pressure-sensitive adhesive composition and pressure-sensitive adhesive sheet DAI NIPPON PRINTING CO., LTD. (JP) 2026-03-24 US disclosed
US-20240141213-A1 GAS GENERATING AGENT, PRESSURE-SENSITIVE ADHESIVE COMPOSITION AND PRESSURE-SENSITIVE ADHESIVE SHEET DAI NIPPON PRINTING CO., LTD. (JP) 2024-05-02 US disclosed
CN-116615415-A Gas generating agent, adhesive composition, and adhesive sheet 大日本印刷株式会社 2023-08-18 CN disclosed
WO-2022138703-A1 GAS-GENERATING AGENT, ADHESIVE COMPOSITION, AND ADHESIVE SHEET 大日本印刷株式会社 2022-06-30 WO disclosed
US-10017479-B2 Process to make non nucleosidal reverse transcriptase inhibitors (NNRTI) for the treatment of HIV ROSOCHA GREGORY (CA) 2018-07-10 US disclosed
US-10017479-B2 Process to make non nucleosidal reverse transcriptase inhibitors (NNRTI) for the treatment of HIV ROSOCHA GREGORY (CA) 2018-07-10 US disclosed
US-10017479-B2 Process to make non nucleosidal reverse transcriptase inhibitors (NNRTI) for the treatment of HIV ROSOCHA GREGORY (CA) 2018-07-10 US disclosed
US-4108663-A MULTILAYER FUJI PHOTO FILM CO., LTD. (JP) 1978-08-22 US disclosed
US-4063950-A DEVELOPMENT INHIBITOR RELEASING COMPOUND, SILVER HALIDE EMULSIONS ON KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1977-12-20 US disclosed
US-4049455-A DEVELOPMENT INHIBITOR RELEASING COMPOUND KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1977-09-20 US disclosed
US-4010035-A DEVELOPMENT INHIBITOR RELEASING COMPOUND, HARDENER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1977-03-01 US disclosed
US-3961959-A DEVELOPMENT RELEASING INHIBITOR KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1976-06-08 US disclosed
US-3958993-A SULFUR CONTAINING ORGANIC COMPOUND KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1976-05-25 US disclosed
US-3938996-A Process for developing light-sensitive silver halide photographic materials KONISHIROKU PHOTO INDUSTRY CO. LTD. (JA) 1976-02-17 US disclosed
US-3932185-A SILVER HALIDE EMULSIONS, MERCAPTAN-TYPE COMPOUND REACTION WITH OXIDIZED AROMATIC AMINE KONISHIROKU PHOTO INDUSTRY CO., INC. (JA) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10017479-B2 Process to make non nucleosidal reverse transcriptase inhibitors (NNRTI) for the treatment of HIV DNTT, NNMT, PNP ALDH1A1 1878/4885ADRB2 3068/4885HSD17B10 2226/4885
US-12584046-B2 Gas generating agent, pressure-sensitive adhesive composition and pressure-sensitive adhesive sheet COL2A1, COL1A1, COL14A1 ALDH1A1 1998/4885ADRB2 782/4885HSD17B10 4339/4885
US-20240141213-A1 GAS GENERATING AGENT, PRESSURE-SENSITIVE ADHESIVE COMPOSITION AND PRESSURE-SENSITIVE ADHESIVE SHEET CDH1, EPCAM, FN1 ALDH1A1 2907/4885ADRB2 2259/4885HSD17B10 4330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.