Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7868339 | 0.88 | PTGS2 (0.45) | PTGS2PTGS1 | |
| SCHEMBL7773790 | 0.78 | PTGS2 (0.42) | PTGS2PTGS1 | |
| Benzenesulfonamide SCHEMBL7049598 | 0.73 | PTGS2 (0.61) | PTGS2PTGS1 | |
| SCHEMBL7872129 | 0.68 | PTGS2 (0.76) | PTGS2PTGS1 | |
| SCHEMBL7932077 | 0.67 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL7860657 | 0.66 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL8350247 | 0.66 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL8346344 | 0.66 | PTGS2 (0.55) | PTGS2PTGS1 | |
| Pyridine SCHEMBL7918818 | 0.65 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL8348990 | 0.64 | PTGS2 (0.54) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998016227-A9 | METHOD OF USING CYCLOOXYGENASE-2 INHIBITORS IN THE TREATMENT AND PREVENTION OF NEOPLASIA | — | 1998-07-30 | — | — | WO | disclosed |