Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 8/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928034 | 0.87 | SMN1; SMN2 (0.32) | CYP1A2CYP2C19SMN1; SMN2CYP2C9RAB9A | |
| SCHEMBL9753847 | 0.82 | LMNA (0.35) | LMNACYP1A2TSHRCYP2C19ESR1 | |
| SCHEMBL16670075 | 0.74 | RAB9A (0.40) | LMNACYP1A2MAPK1SMN1; SMN2RAB9A | |
| SCHEMBL8581687 | 0.74 | PTPN2 (0.36) | — | |
| SCHEMBL5952565 | 0.74 | NPC1 (0.50) | TSHRSMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL2356948 | 0.74 | PRSS1 (0.42) | LMNATSHRCYP2C19MAPK1RAB9A | |
| SCHEMBL1454369 | 0.73 | CA1 (0.54) | LMNACYP1A2TSHRCYP2C19ESR1 | |
| SCHEMBL16553458 | 0.72 | ALDH1A1 (0.46) | RAB9AMAPTNPC1ALDH1A1 | |
| SCHEMBL6027320 | 0.72 | ELANE (0.44) | LMNASTSRAB9AMAPTALDH1A1 | |
| SCHEMBL3111477 | 0.72 | CA1 (0.41) | LMNARAB9AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5746997-A | Radiohalogenation of oligonucleotides via trialkylstannylaryl conjugates | EPOCH PHARMACEUTICALS, INC. (US) | 1998-05-05 | — | — | US | claimed |
| US-5746997-A | Radiohalogenation of oligonucleotides via trialkylstannylaryl conjugates | EPOCH PHARMACEUTICALS, INC. (US) | 1998-05-05 | — | — | US | disclosed |