Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 12/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8609905 | 0.88 | HTR1F (0.51) | OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL8585768 | 0.87 | NPC1 (0.52) | — | |
| SCHEMBL8583210 | 0.86 | HTR1A (0.56) | — | |
| SCHEMBL8613872 | 0.83 | SIGMAR1 (0.48) | OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL8583266 | 0.80 | RAB9A (0.44) | — | |
| SCHEMBL8582998 | 0.76 | DRD2 (0.52) | SIGMAR1 | |
| SCHEMBL7010718 | 0.75 | HTR1F (0.77) | — | |
| SCHEMBL17512173 | 0.75 | SIGMAR1 (0.67) | OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL8586783 | 0.74 | CHRM1 (0.48) | SIGMAR1 | |
| SCHEMBL8585332 | 0.73 | SIGMAR1 (0.55) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998020875-A1 | 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-05-22 | — | — | WO | disclosed |