Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.42 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYB5R3 | P00387 | 1/20 | 0.35 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiouracil SCHEMBL546068 | 0.84 | — | — | |
| Thiouracil SCHEMBL9172 | 0.84 | — | — | |
| Thiouracil SCHEMBL27922231 | 0.82 | — | — | |
| Thiouracil SCHEMBL30091289 | 0.82 | — | — | |
| Uracil SCHEMBL28120281 | 0.76 | TP53 (0.83) | TP53CRBNTAS2R38SMN1; SMN2MMP2 | |
| Thiouracil SCHEMBL7804101 | 0.75 | TP53 (0.79) | TP53CRBNTAS2R38SMN1; SMN2MMP2 | |
| Thiouracil SCHEMBL28095966 | 0.73 | TP53 (0.76) | TP53CRBNTAS2R38SMN1; SMN2MMP2 | |
| Thiouracil SCHEMBL18815516 | 0.73 | TP53 (0.76) | TP53CRBNTAS2R38SMN1; SMN2MMP2 | |
| Thiouracil SCHEMBL27970384 | 0.73 | TP53 (0.76) | TP53CRBNTAS2R38SMN1; SMN2MMP2 | |
| Thiouracil SCHEMBL28205719 | 0.72 | TP53 (0.73) | TP53CRBNTAS2R38SMN1; SMN2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716797-A | CONTAINING THIOGLYCEROL, 2-MERCAPTOETHANOL AND/OR 2-MERCAPTOETHANESULFONIC ACID OR ITS SALT AS CREATINE KINASE REACTIVATOR | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-10 | — | — | US | disclosed |