Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 3/20 | 0.38 |
| ▸ | BCAT1 | P54687 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.34 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8612009 | 0.79 | BCAT2 (0.41) | ALDH1A1KMT2AKDM4EBCAT2BCAT1 | |
| SCHEMBL8566733 | 0.73 | ALDH1A1 (0.57) | ALDH1A1KMT2AKDM4EBCAT2BCAT1 | |
| SCHEMBL8612850 | 0.72 | BCAT2 (0.40) | ALDH1A1KMT2AKDM4EBCAT2BCAT1 | |
| SCHEMBL8525560 | 0.72 | ALDH1A1 (0.50) | ALDH1A1KMT2AKDM4EGAASMN1; SMN2 | |
| SCHEMBL5732851 | 0.69 | ALDH1A1 (0.39) | ALDH1A1KMT2AKDM4EBCAT2BCAT1 | |
| SCHEMBL8612943 | 0.69 | BCAT2 (0.37) | ALDH1A1KMT2AKDM4EBCAT2BCAT1 | |
| SCHEMBL6802264 | 0.68 | BCAT2 (0.42) | ALDH1A1KMT2AKDM4EBCAT2BCAT1 | |
| SCHEMBL7471937 | 0.66 | BCAT1 (0.40) | ALDH1A1KMT2AKDM4EBCAT2BCAT1 | |
| SCHEMBL8820735 | 0.66 | ALDH1A1 (0.43) | ALDH1A1KMT2AKDM4EBCAT2BCAT1 | |
| SCHEMBL10696215 | 0.65 | HSP90AA1 (0.43) | ALDH1A1KMT2AKDM4EBCAT2BCAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0836594-A1 | BENZYLHYDROXYLAMINES AND INTERMEDIATES USED TO PREPARE THEM | BASF AKTIENGESELLSCHAFT (DE) | 1998-04-22 | — | — | EP | disclosed |