Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620705 | 0.93 | MTNR1A (0.34) | KDM1AMAOAMAOBACHEMTNR1B | |
| SCHEMBL8644235 | 0.91 | PPARA (0.35) | MAPK1MAPK14 | |
| SCHEMBL8647745 | 0.82 | MAPK1 (0.39) | MAPK1MAPK14KDM1AMAOAMAOB | |
| SCHEMBL7715113 | 0.79 | HCRTR1 (0.39) | KDM1AMAOAMAOBACHEHTR7 | |
| SCHEMBL7259713 | 0.79 | HCRTR1 (0.39) | KDM1AMAOAMAOBACHEHTR7 | |
| SCHEMBL8617783 | 0.77 | MTNR1A (0.39) | KDM1AMAOAMAOBACHEMTNR1B | |
| SCHEMBL7715098 | 0.77 | ACHE (0.48) | KDM1AMAOAMAOBACHE | |
| SCHEMBL7263724 | 0.77 | ACHE (0.48) | KDM1AMAOAMAOBACHE | |
| SCHEMBL7709306 | 0.71 | MTNR1B (0.36) | MTNR1B | |
| SCHEMBL7721427 | 0.71 | MTNR1B (0.36) | MTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998052913-A2 | LEUKOTRIENE B4 ANTAGONISTS, IN PARTICULAR 3-OXA-TETRAHYDRONAPHTHALENE-LTB4 ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-11-26 | — | — | WO | disclosed |