SCHEMBL862247

SCHEMBL862247

Cc1ccc2nc3cc(C)c(C)cc3cc2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.52
NCK1 P16333 1/20 0.48
BACE1 P56817 1/20 0.48
NQO2 P16083 2/20 0.48
TERT O14746 1/20 0.48
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
PSMB5 P28074 2/20 0.46
CYP2A6 P11509 3/20 0.44
ALDH1A1 P00352 2/20 0.44
PDE3B Q13370 2/20 0.43
PDE3A Q14432 2/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C19 P33261 1/20 0.43
MITF O75030 1/20 0.41
MAPT P10636 1/20 0.41
NFKB1 P19838 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2371400 0.89 CYP1A2 (0.62) CYP1A2NCK1BACE1NQO2MEN1
SCHEMBL862528 0.87 CYP1A2 (0.54) CYP1A2NCK1BACE1NQO2TERT
SCHEMBL9755319 0.84 CYP1A2 (0.65) CYP1A2NCK1BACE1NQO2TERT
SCHEMBL9755344 0.83 TERT (0.64) CYP1A2NQO2TERTMEN1KMT2A
SCHEMBL862359 0.80 MEN1 (0.56) CYP1A2NCK1BACE1NQO2MEN1
SCHEMBL29660632 0.78 ALDH1A1 (0.65) CYP1A2NQO2TERTMEN1KMT2A
SCHEMBL4641875 0.78 ALDH1A1 (0.65) CYP1A2NQO2TERTMEN1KMT2A
SCHEMBL4427125 0.78 NQO2 (0.65) CYP1A2NCK1BACE1NQO2MEN1
SCHEMBL14702032 0.77 NCK1 (0.57) CYP1A2NCK1BACE1NQO2TERT
SCHEMBL3835603 0.77 CYP1A2 (0.50) CYP1A2NCK1BACE1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180053868-A1 PHOTOELECTRIC CONVERSION DEVICE HAVING REFLECTION PLATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-22 US disclosed
US-20180053868-A1 PHOTOELECTRIC CONVERSION DEVICE HAVING REFLECTION PLATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-22 US disclosed
US-20170162808-A1 PHOTOELECTRIC CONVERSION DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-08 US disclosed
US-20170162808-A1 PHOTOELECTRIC CONVERSION DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-08 US disclosed
US-20160372675-A1 MACROMOLECULAR COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-12-22 US disclosed
US-9512149-B2 Reactive compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-12-06 US disclosed
US-9512149-B2 Reactive compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-12-06 US disclosed
US-9472763-B2 Macromolecular compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-10-18 US disclosed
US-9396831-B2 Polymer compound and electronic device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-07-19 US disclosed
US-9396831-B2 Polymer compound and electronic device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-07-19 US disclosed
US-20120205593-A1 POLYMERIC COMPOUND AND ELECTRONIC ELEMENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-16 US disclosed
US-8142908-B2 Polymer light-emitting material comprising a conjugated polymer and compound exhibiting light emission from the triplet excited state and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-27 US disclosed
US-20120008068-A1 POLYMER COMPOUND AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-12 US disclosed
US-8012603-B2 Polyanilines; strong fluorescence and large charge transporting properties SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-09-06 US disclosed
US-20080138651-A1 Polyanilines; strong fluorescence and large charge transporting properties SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-06-12 US disclosed
US-20080118773-A1 Complex Composition, Polymer Complex Compound And Polymer Light-Emitting Device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-05-22 US disclosed
US-20080003422-A1 Polymer Compound, Polymer Thin Film and Polymer Thin Film Device Using the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-01-03 US disclosed
US-20070051922-A1 Polymer light-emitting material and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-08 US disclosed
US-20070040164-A1 Polymer complex compound and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-02-22 US disclosed
WO-1991005770-A1 POTENTIAL ANTICANCER AGENTS DERIVED FROM ACRIDINE SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1991-05-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080138651-A1 Polyanilines; strong fluorescence and large charge transporting properties BRS3, SLC43A1, MRPS23 CYP1A2 3318/4885NCK1 2647/4885BACE1 4235/4885
US-20160372675-A1 MACROMOLECULAR COMPOUND EXOSC4, TRPC6, MRPS22 CYP1A2 4239/4885NCK1 1418/4885BACE1 4021/4885
US-20120205593-A1 POLYMERIC COMPOUND AND ELECTRONIC ELEMENT ARPC2, AXIN2, EMC2 CYP1A2 180/4885NCK1 2480/4885BACE1 2780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.