SCHEMBL862356

SCHEMBL862356

Cc1cc(C)c2cccnc2c1C

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 4/20 0.63
CCR8 P51685 4/20 0.63
L3MBTL1 Q9Y468 3/20 0.59
NPC1 O15118 1/20 0.59
HSP90AA1 P07900 1/20 0.59
PSMD14 O00487 2/20 0.53
COPS5 Q92905 2/20 0.53
SLC6A2 P23975 1/20 0.53
HTT P42858 1/20 0.53
SLC40A1 Q9NP59 4/20 0.48
CCR5 P51681 2/20 0.47
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
PRMT5 O14744 1/20 0.42
LMNA P02545 1/20 0.41
BRD4 O60885 1/20 0.40
BLM P54132 1/20 0.40
ADORA3 P0DMS8 1/20 0.39
ADORA2A P29274 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL862349 0.83 L3MBTL1 (0.65) CCR1CCR8L3MBTL1NPC1HSP90AA1
SCHEMBL18515967 0.82 L3MBTL1 (0.53) CCR1CCR8L3MBTL1NPC1HSP90AA1
SCHEMBL27806764 0.82 HTT (0.58) CCR1CCR8L3MBTL1NPC1HSP90AA1
SCHEMBL21130135 0.82 L3MBTL1 (0.58) CCR1CCR8L3MBTL1NPC1HSP90AA1
SCHEMBL14824894 0.82 CCR1 (0.58) CCR1CCR8L3MBTL1NPC1HSP90AA1
SCHEMBL23954445 0.82 HTT (0.56) CCR1CCR8L3MBTL1NPC1HSP90AA1
SCHEMBL17046868 0.80 HTT (0.59) CCR1CCR8L3MBTL1NPC1HSP90AA1
SCHEMBL318630 0.80 HTT (0.59) CCR1CCR8L3MBTL1NPC1HSP90AA1
SCHEMBL29577465 0.80 HTT (0.59) CCR1CCR8L3MBTL1NPC1HSP90AA1
SCHEMBL21297755 0.80 HSP90AA1 (0.73) CCR1CCR8L3MBTL1NPC1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210238415-A1 POLYMER, METAL REMOVAL COMPOSITION, AND METHOD OF REMOVING METAL IONS INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2021-08-05 US disclosed
EP-3498717-A1 COMPOSITION FOR HARDENING SOFT TISSUE The Catholic University of Korea Industry-Academic Cooperation Foundation (KR) 2019-06-19 EP disclosed
US-20180053868-A1 PHOTOELECTRIC CONVERSION DEVICE HAVING REFLECTION PLATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-22 US disclosed
US-20180053868-A1 PHOTOELECTRIC CONVERSION DEVICE HAVING REFLECTION PLATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-22 US disclosed
US-20170365798-A1 FLUORINATED AROMATIC SMALL MOLECULES AS FUNCTIONAL ADDITIVES FOR DISPERSION OF CONDUCTIVE POLYMERS Heraeus Deutschland GmbH & Co. KG (DE) 2017-12-21 US disclosed
WO-2017133517-A1 PHOSPHAMIDE DERIVATIVE, METHOD FOR MANUFACTURING THE SAME, AND USES THEREOF 四川海思科制药有限公司 2017-08-10 WO disclosed
US-20170162808-A1 PHOTOELECTRIC CONVERSION DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-08 US disclosed
US-20170162808-A1 PHOTOELECTRIC CONVERSION DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-08 US disclosed
US-20160372675-A1 MACROMOLECULAR COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-12-22 US disclosed
US-9512149-B2 Reactive compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-12-06 US disclosed
US-20090048294-A1 HIF-1 ALPHA ACTIVATING AGENT UNIVERSITY OF SEOUL FOUNDATION OF INDUSTRIAL AND ACADEMIC COOPERATION (KR) 2009-02-19 US disclosed
US-20090029986-A1 N-AROYL CYCLIC AMINES SMITHKLINE BEECHAM P.L.C. 2009-01-29 US disclosed
US-20090012073-A1 N-AROYL CYCLIC AMINES SMITHKLINE BEECHAM P.L.C. 2009-01-08 US disclosed
US-7432270-B2 N-aroyl cyclic amines SMITHKLINE BEECHAM P.L.C. (GB) 2008-10-07 US disclosed
US-20080138651-A1 Polyanilines; strong fluorescence and large charge transporting properties SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-06-12 US disclosed
US-20080118773-A1 Complex Composition, Polymer Complex Compound And Polymer Light-Emitting Device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-05-22 US disclosed
US-20080003422-A1 Polymer Compound, Polymer Thin Film and Polymer Thin Film Device Using the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-01-03 US disclosed
US-20070103059-A1 Composition and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-10 US disclosed
US-20070051922-A1 Polymer light-emitting material and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-08 US disclosed
US-20070040164-A1 Polymer complex compound and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090012073-A1 N-AROYL CYCLIC AMINES AANAT, MAOA, MAOB CCR1 2597/4885CCR8 2065/4885L3MBTL1 4838/4885
US-20080138651-A1 Polyanilines; strong fluorescence and large charge transporting properties BRS3, SLC43A1, MRPS23 CCR1 70/4885CCR8 403/4885L3MBTL1 3114/4885
US-20090029986-A1 N-AROYL CYCLIC AMINES AANAT, MAOA, MAOB CCR1 2597/4885CCR8 2065/4885L3MBTL1 4838/4885
US-20170365798-A1 FLUORINATED AROMATIC SMALL MOLECULES AS FUNCTIONAL ADDITIVES FOR DISPERSION OF CONDUCTIVE POLYMERS SLCO4C1, SLCO2B1, SLCO2A1 CCR1 1557/4885CCR8 3261/4885L3MBTL1 4867/4885
US-20090048294-A1 HIF-1 ALPHA ACTIVATING AGENT HIF1AN, HIF1A, P4HA1 CCR1 3465/4885CCR8 3998/4885L3MBTL1 650/4885
US-20160372675-A1 MACROMOLECULAR COMPOUND EXOSC4, TRPC6, MRPS22 CCR1 288/4885CCR8 1548/4885L3MBTL1 3981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.