Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 6/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.54 |
| ▸ | NOS3 | P29474 | 2/20 | 0.49 |
| ▸ | NOS1 | P29475 | 2/20 | 0.49 |
| ▸ | FDPS | P14324 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5498490 | 0.83 | NOS3 (0.49) | PRMT6EPHX2CYP11B1CYP11B2NOS3 | |
| SCHEMBL8625514 | 0.82 | CYP11B1 (0.50) | PRMT6EPHX2CYP11B1CYP11B2FDPS | |
| SCHEMBL29373657 | 0.82 | FDPS (0.53) | PRMT6EPHX2CYP11B1CYP11B2FDPS | |
| SCHEMBL402768 | 0.82 | FDPS (0.53) | PRMT6EPHX2CYP11B1CYP11B2FDPS | |
| SCHEMBL14079723 | 0.80 | NOS3 (0.47) | PRMT6EPHX2CYP11B1CYP11B2NOS3 | |
| SCHEMBL13778372 | 0.80 | NOS3 (0.49) | PRMT6EPHX2CYP11B1CYP11B2NOS3 | |
| SCHEMBL10271979 | 0.79 | CYP11B1 (0.54) | CYP11B1CYP11B2FDPSCYP3A4PDE10A | |
| SCHEMBL3665839 | 0.79 | PRMT6 (0.45) | PRMT6EPHX2CYP11B1CYP11B2NOS3 | |
| SCHEMBL27649705 | 0.78 | ADH1B (0.55) | CYP11B1CYP11B2FDPSPDE10AATM | |
| SCHEMBL1252083 | 0.77 | PRMT6 (0.73) | PRMT6EPHX2NOS1CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3642303-B1 | COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES | KYULUX INC (JP) | 2021-04-14 | — | — | EP | disclosed |
| US-5767132-A | CENTRAL NERVOUS SYSTEM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-06-16 | — | — | US | disclosed |