Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | NAT1 | P18440 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8759075 | 0.89 | MCL1 (0.41) | MCL1FFAR4ALDH1A1HPGDHTT | |
| SCHEMBL8632286 | 0.87 | KIT (0.45) | ALDH1A1MEN1KMT2ALMNACA12 | |
| SCHEMBL8632837 | 0.86 | LMNA (0.51) | MCL1FFAR4ALDH1A1MEN1KMT2A | |
| SCHEMBL8631659 | 0.85 | NAT1 (0.53) | LMNANAT1PTPN2PTPN1KDM4E | |
| SCHEMBL8629484 | 0.85 | MAP2K4 (0.45) | PTPN1PTPN5 | |
| SCHEMBL8630028 | 0.85 | ALDH1A1 (0.45) | MCL1FFAR4ALDH1A1HTTLMNA | |
| SCHEMBL8627985 | 0.82 | FFAR4 (0.50) | FFAR4ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL8632810 | 0.82 | STAT3 (0.42) | MCL1FFAR4ALDH1A1KMT2AMCOLN3 | |
| SCHEMBL8627771 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HPGDHTTMEN1KMT2A | |
| SCHEMBL8628067 | 0.81 | SMN1; SMN2 (0.43) | FFAR4ALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |